In this sequel to 'Desperado', a Mexican drug lord pretends to overthrow the Mexican government, and is connected to a corrupt CIA agent who at that time, demands retribution from his worst enemy to carry out the drug lord's uprising against the government.
Once Upon a Time in Mexico is a 2003 action film written, edited and directed by Robert Rodriguez. It is the final film in the "Mariachi Trilogy", which also includes El Mariachi and Desperado. Antonio Banderas reprises his role as El Mariachi. The film also stars Johnny Depp, Salma Hayek, Willem Dafoe, Enrique Iglesias, Mickey Rourke, Eva Mendes and Rubén Blades.